C-Reactive Protein (CRP) belongs to the β-globulin family of plasma proteins and derives its name from its ability to precipitate a group C polysaccharide of pneumococcus in the presence of Ca2+.
Although its physiological function is unknown, serum levels of CRP are elevated in a wide variety of acute and chronic inflammatory conditions. These conditions include most bacterial and some viral infections, rheumatic fever, rheumatoid arthritis, and many collagen diseases. CRP serum levels are also valuable in the detection and evaluation of tissue injury, acute myocardial infarction, transplant rejection, and several malignant disorders.
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