C-Reactive protein (CRP) is one of the primary acute phase proteins that elevate during an inflammatory response. It is synthesized primarily by liver hepatocytes, although it is also produced in several other types of cells. It is a non-glycosylated molecule, composed of 5 identical subunits. The physiological role of CRP is not known, but plasma levels are elevated in a variety of acute and chronic inflammatory conditions. These conditions include most bacterial infections, some viral infections, as well as rheumatic fever, rheumatoid arthritis, and several collagen diseases. Clinical tests for CRP are among the most commonly performed to detect and assess inflammation.
CRP and anti-CRP antibodies from Scripps Laboratories are suitable for use in diagnostic assay development and in a variety of research applications.
- Inflammation Calibrators & Controls
- CRP Protein for Detection of Anti-CRP Autoimmune Antibodies
- Antigen for Anti-CRP Antibody Development