Glycosylated Whole Molecule
Expressed in Mammalian Cells
No Affinity Tags
Large Lot Sizes
Recombinant Human Follicle Stimulating Hormone (hFSH) is the first product released by the Recombinant Protein Development Team at Scripps Laboratories. Expressed in a mammalian cell culture system, our Recombinant hFSH is a glycosylated, whole molecule form of hFSH.
Scripps is known worldwide for providing the highest-quality and best-performing native human hormones. Decades of experience have given our scientific team a thorough understanding of what it takes to purify human hormones, while maintaining protein integrity and preserving activity across multiple assay platforms. Plying this expertise to our recombinant proteins, our aim is to produce the best-performing recombinant hormones available anywhere.
Our purification expertise allows us to produce recombinant proteins without the use of affinity tags. Commonly used tags, such as polyhistidine and glutathione S-transferase, make purification simpler, but they can have an adverse effect on the structure and function of the expressed protein, leading to poor performance in a variety of assay systems. Producing the unmodified, intact protein allows our protein purification experts to isolate a recombinant form of hFSH that resembles the native form as closely as possible.
Our Recombinant hFSH has been assayed on multiple clinical analyzers and it exhibits activity that is comparable to that of native hFSH.* As a recombinant protein, no other pituitary hormones are present in the starting material of our hFSH. This results in a highly-purified product that is ≥95% pure by SDS-PAGE and is free from the contaminating hormones that are an inherent problem with native hFSH.
At Scripps Laboratories we understand the importance of producing high-quality recombinant proteins that closely resemble their native counterparts in multiple applications. You can be sure recombinant proteins from Scripps Laboratories have been tested thoroughly and will perform consistently, as described on the Certificates of Conformance. To those who have tried other recombinant proteins, but found they did not perform as well as expected, our message is simply this: You haven’t tried recombinant proteins from Scripps Laboratories.
Bulk lots of high-quality Recombinant hFSH are available now: Recombinant hFSH, ≥95%
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*Analyses were performed on the Siemens Centaur CP and Beckman Access clinical immunoassay systems.