C-Reactive protein (CRP) was first associated with infection circa 1930 and, today, elevated plasma levels of CRP are known to correlate with many types of infections and disease states. It is one of the key acute phase proteins, released in response to inflammatory cytokines, and plasma CRP concentrations often correspond with disease severity. CRP is composed of 5 identical, non-glycosylated subunits and it is synthesized primarily by liver hepatocytes, although it is also produced in adipocytes, endothelial cells, lymphocytes, macrophages, and smooth muscle cells. In clinical diagnostics, CRP tests are widely used to help diagnose and monitor a wide variety of infections and diseases.
Two grades of purified CRP are available, in addition to monoclonal and polyclonal antibodies, for your research and assay development needs. Browse below to learn more or to purchase now.
- Plasma Protein Calibrator & Control Development
- Purified CRP for Antibody Detection
- Immunogen for Antibody Development