Scripps Laboratories

Comparison of Hormone Reference Preparations

Abbr.Reference Prep.PotencyDefinition of Potency
hFSH__ 1st IRP-hMG (1960) No official units Activity as "mg" 1st IRP-hMG
  2nd IRP-hMG (1964) 40 IU/ampule 1 IU = 7mg 1st IRP-hMG
  1st IRP-Pituitary FSH/LH for Bioassay (69/104) 10 IU/ampule Approximately 20 IU 2nd IRP-hMG
  2nd IRP-Pituitary FSH/LH for Bioassay (78/549) 10 IU/ampule Based on 69/104
  1st IS-Pituitary FSH (83/575) 80 IU/ampule 5 - 80 IU (78/549), depending on assay

hGH 1st IRP (66/217) 2.2 IU/mg for pure hormone Equivalent to NIAMDD-hGH-RP1
  1st IS (80/505) 4.4 IU/ampule Based on 66/217

hLH 1st IRP-hMG (1960) No official units Activity as "mg" 1st IRP-hMG
  2nd IRP-hMG (1964) 40 IU/ampule 1 IU = 2mg 1st IRP-hMG
  1st IRP-Pituitary FSH/LH for Bioassay (69/104) 25 IU/ampule Approximately 50 IU 2nd IRP-hMG
  2nd IRP-Pituitary FSH/LH for Bioassay (78/549) 25 IU/ampule Based on 69/104
  1st IRP-Pituitary LH (68/40) 77 IU/ampule 15 - 75 IU (69/104), depending on assay
  2nd IS-Pituitary LH (80/552) 35 IU/ampule 25 - 45 IU (68/40), depending on assay

hPRL 1st IRP (75/504) 30 IU/mg for pure hormone  
  2nd IS (83/562) 53 mIU/ampule 53 mIU 1st IRP (75/504)
  3rd IS (84/500) 53 mIU/ampule 53 mIU 2nd IS (83/562)

hTSH 1st IRP,human TSH (68/38) 150 mIU/ampule By definition
  2nd IRP,human TSH (80/558) 37 mIU/ampule

36 - 46 mIU (68/38), depending on assay

Technical Info

Hormone Data